Our physician-scientists are studying a novel approach to treating SIOD that’s a potential cure for the kidney disease and immune problems caused by SIOD. This treatment is a two-transplant approach—a haploidentical stem cell transplant, which provides your child with a new immune system, followed by a kidney transplant from the same donor, usually a parent. Since your child’s new immune system recognizes its new kidney, it is less likely to reject it.
Have you tried this approach with other children? How are they doing?
Of the first three children treated with this method at Stanford Children’s Health, all three were successfully transplanted and all three achieved full donor engraftment—meaning the transplanted stem cells grew into healthy cells, including those that are part of the immune system.. The three children, two of whom are siblings, achieved normal kidney function without the use of long-term anti-rejection medicines.